Although powder-coated MDF is a durable, seamless surface, it is not completely impervious to stains and damage from moisture or heat. Simply take the same precautions you would with any wood furniture.
Avoid dragging sharp or rough objects across the surface of your furniture. Use adhesive felt pads, trivets, coasters and placemats to help prevent scratches.
Use a slightly damp cloth to clean as needed. Wipe dry.
For spot cleaning, use an all-purpose cleaner or a solution of water and mild detergent. Wipe dry.